[lil_dids]

It depends on how much time you want to dedicate to it. If you are just in it for some fun, make sure your lineup is filled with players that play everyday. (You only get points when they play.) If you have guys that share positions, you won't get much from them. It is early in the season, so it is tough to tell whether you should be looking to make any changes by dropping or adding players.

Watch out for injuries or any other reason your guys might not be in the lineup. If you keep your eyes on the schedules, you can change your lineup to work around days that teams have off. (This takes some time, and you can get burned if you forget to change back after the off day.)

You can edit the lineup each day if you want. Watch the stats of your players, and the ones on the bench (BN). You only get points for the active players, so if your bench players are doing better, change them for somebody else that is not performing as well.

Baseball has millions of stats that you can compare if you have the time or inclination. Usually the Yahoo rankings are a pretty good starting point, but making your own calls is what makes it fun. Keep an eye out for news updates about your players, they usually indicate that something about thier status has changed. (Injury, trade, sent to minors, etc.)

You don't need to change the lineup all the time. The season is long, and you will get a hang of it as you go along.