Best moves:
Trading Polanco for Uggla at the start of the season.
Dropping Pierre and picking up Nate McLouth at the start of the season
Dropping Bronson Arroyo after his first start (not a huge move, but ended up ok)
Chen Mieng Wong with 15th pick
Worst moves:
Dropping Geovany Soto at the beginning of the season instead of keeping him, or trying to trade him or Mauer
Drafting Liriano with my 10th pick
(only used him for .2 innings though)